慢性丙型肝炎患者的血清维生素D与严重肝纤维化相关性研究:系统性的荟萃分析(英文)     

Yue-qiu LUO  Xiao-xing WU  Zong-xin LING  Yi-wen CHENG  Li YUAN  Charlie XIANG 《Journal of Zhejiang University. Science. B》2014,(10)

研究目的:利用meta分析方法来探索慢性丙型肝炎患者低血清维生素D水平与严重肝纤维化相关性。创新要点:丙型病毒性肝炎病人的低血清维生素D水平与严重肝纤维化并不一定有相关性。研究方法:结合已发表的临床研究数据,采用荟萃分析方法,定量分析低血清维生素D水平与慢性丙型肝炎患者严重肝纤维化相关性(图2;表2)。重要结论:此荟萃分析对于认识丙型肝炎病人低血清维生素D水平与肝纤维化严重程度的相关性有重要意义,对未来相关临床研究具有指导意义。  相似文献   

Association between serum vitamin D and severity of liver fibrosis in chronic hepatitis C patients: a systematic meta-analysis     

Yue-qiu Luo  Xiao-xing Wu  Zong-xin Ling  Yi-wen Cheng  Li Yuan  Charlie Xiang 《Journal of Zhejiang University. Science. B》2014,15(10):900-906

To conduct a systematic review of group studies assessing the association of serum vitamin D status with the severity of liver fibrosis in chronic hepatitis C patients using meta-analysis. The relevant research literatures were identified by searching PubMed and EMBASE databases prior to October 2013 with no restrictions. We included group studies that reported odds ratio (OR) estimates with 95% confidence intervals (CIs) or a mean with standard deviation (SD) for the association between serum vitamin D status and the severity of liver fibrosis in chronic hepatitis C patients. Approximately 8321 participants from several countries were included in this analysis. Six studies on serum vitamin D status and the severity of liver fibrosis were included in this meta-analysis. ORs with 95% CIs were extracted from four studies and the pooled ORs were 0.866 (95% CI, 0.649 to 1.157). The means with SDs were extracted from three studies and the pooled means were −0.487 (95% CI, −0.659 to −0.315). There was statistically significant heterogeneity among the mean data extracted studies (P=0.029; I ²=71.8%) but not among the OR data extracted studies (P=0.061; I ²=55.6%). Finally, results from the mean data extracted studies suggest that lower serum vitamin D is a risk factor for the severity of liver fibrosis in chronic hepatitis C patients. However, there is no conclusive evidence on this association because of inconsistencies between the OR data extracted studies and the mean data extracted studies.  相似文献   

Abject Magic: Reasoning Madness in Justine Larbalestier’s Magic or Madness Trilogy     

Troy Potter 《Children‘s Literature in Education》2014,45(3):255-270

This paper explores the representation of magic and madness in Justine Larbalestier’s Magic or Madness trilogy (2005–2007). Throughout the series, magic is constructed as an abject and disabling force that threatens to disable magic-wielders, either through madness or death. Despite being represented as a ubiquitous force, the consequences of magic are gendered, and the female protagonist of the trilogy, Reason, sets out to remove the threat of magic. The intersections between ableist, magical and feminine discourses are explored via a feminist disability politics and Kristeva’s concept of abjection. While, at times, the trilogy challenges the ability/disability binary schism, the narrative closure reaffirms dualistic constructions of reason/madness, ability/disability, reality/fantasy and masculine/feminine. Thus, rather than redressing social attitudes towards mental illness and critiquing normative constructions of disability and the other, Larbalestier’s trilogy reaffirms dualistic and normative constructions of mental illness.  相似文献   

BOOK REVIEWS     

Clare Pettitt  Simon J. Potter  David Lloyd Smith 《Media History》2013,19(4):441-447

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Faculty Collaboration to Improve Equity,Access, and Inclusion in Higher Education     

Charlie Bernacchio  Flynn Ross  Kimberley Robinson Washburn  Jean Whitney  Diane R. Wood 《Equity & Excellence in Education》2013,46(1):56-66

This article documents the Critical Friends Group (CFG) process five university colleagues used to blend the theoretical frameworks of Universal Design for Learning (Rose & Meyer, 2002 Rose, D. and Meyer, A. 2002. Teaching every student in the digital age: Universal design for learning, Alexandria, VA: Association for Supervision and Curriculum Development.  [Google Scholar]) and Interactive Phase Theory (McIntosh, 1990 McIntosh, P. 1990. Interactive phases of curricular and personal re-vision with regard to race, Wellesley, MA: Wellesley College Center for Research on Women. (Paper # 219) [Google Scholar]) as tools to increase equity and access in our classrooms. Using the CFG reflective approach, the faculty collaboratively reviewed their syllabi and implemented innovations in their classroom practice. This article presents a theory of action that emerged as well as nine tensions related to teaching and participation in a learning community. Implications for equity and access in higher education and future inquiry are presented.  相似文献   

Early Care and Education Matters: A Conceptual Model for Early Childhood Teacher Preparation Integrating the Key Constructs of Knowledge,Reflection, and Practice     

Shulamit N. Ritblatt  Sarah Garrity  Sascha Longstreth  Audrey Hokoda  Nina Potter 《Journal of Early Childhood Teacher Education》2013,34(1):46-62

There has been a great deal of discourse in the field of early care and education concerning the experiences, skills, competencies, and education level needed by early childhood teachers to ensure that quality teaching and learning take place in the early years. The purpose of this article is to describe an early childhood teacher preparation program developed by a Child and Family Development Department at a large, urban, state-funded university in the hopes that we can further the discourse on how the field can ensure quality teaching and learning in both ECE and university classrooms. We propose a conceptual model that is built around three key constructs: knowledge, reflection, and practice and describe our approach to preparing early childhood educators. Using qualitative data from student reflections and course syllabi and quantitative data on the experiences and perceptions of graduating seniors, we hope to present promising practices in early childhood teacher education and provide support for our contention that the quality of early childhood teacher education matters.  相似文献   

Oxygen uptake kinetics in children and adults after the onset of moderate-intensity exercise     

Samantha G. Fawkner  Neil Armstrong  Christopher R. Potter  Joanne R. Welsman 《Journal of sports sciences》2013,31(4):319-326

The literature suggests that the oxygen uptake ( V O 2 ) response to the onset of moderate-intensity exercise may be both mature from childhood and independent of sex. Yet the cardiorespiratory response to exercise and the metabolic profile of the muscle appear to change with growth and deve . lopment and to differ between the sexes. The aim of this study was to investigate further changes in the V O2 kinetic response with age and sex. Participants completed a series of no less than four step change transitions, from unloaded pedalling to a constant work rate corresponding to 80% of their previously determined ventilatory threshold. Each participant's breath-by-breath responses were interpolated to 1 s intervals, time aligned and then averaged. A single exponential model that included a time delay was used to analyse the averaged response following phase 1 (15 s). Participants with parameter confidence intervals more than - 5 s were removed from the sample; the results for the remaining 13 men and 12 women (age 19-26 years), 12 boys and 11 girls (age 11-12 years) were used for statistical analysis. Children had a significantly shorter time constant than adults, both for males (19.0 - 2.0 and 27.9 - 8.6 s respectively; P ? 0.01) and females (21.0 - 5.5 and 26.0 - 4.5 s respectively; P ? 0.05). There were no significant differences in the time constant between the sexes for either adults or children ( P > 0.05). A significant relationship between the time constant and peak V O 2 was found only in adult males ( P ? 0.05). A shorter time constant in children may reflect an enhanced potential for oxidative metabolism.  相似文献   

Food Hawkers: Selling in the Streets from Antiquity to the Present     

Charlie Taverner 《Cultural and Social History》2018,15(1):135-136

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The geography of music preferences     

Charlotta Mellander  Richard Florida  Peter J. Rentfrow  Jeff Potter 《Journal of Cultural Economics》2018,42(4):593-618

Considerable attention has been paid to America’s political and economic divides. These divides revolve around class and location, with more affluent, more educated and denser places leaning more open-minded and liberal and less affluent, less educated and less dense places leaning more conservative. We contend that such divides are also reflected and reinforced by preferences, attitudes and predispositions for culture. More specifically we argue that Americans’ preferences for music will reflect dimensions of these political and economic divides. To test this proposition, our research examines the geographic variation of five key categories of music preferences across 95 of the largest US metropolitan areas. We use factor analysis to identify and map geographic variation of musical preferences, and we use both bivariate correlation analyses and regression analysis to examine the associations between metro-level musical preferences and key economic, demographic, political, and psychological variables. We find that musical preferences generally reflect and reinforce America’s broader economic and political divides.  相似文献   

The potential use of the telephone as an instructional device in external studies     

Geoffrey Potter 《Distance Education》1983,4(1):95-107

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